Intracytoplasmic Sperm Injection (ICSI)

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Fertility Treatment: Intracytoplasmic Sperm Injection (ICSI)

Overview

Deciding to have fertility treatment is a difficult decision. There are several types of fertility treatment available, and many factors related to each one to consider.

Before you rush in undergoing any fertility treatment, you must know enough information about the different types of this treatment.

Furthermore, you should deal with a trusted clinic to ensure that you are qualified for fertility treatment and what is the most appropriate procedure according to your condition.

Studies indicate that 80-90% of couples will get pregnant within one year, without the need for assisted reproduction.

However, the specialist doctors recommend fertility treatment such as In Vitro Fertilisation(IVF) or Intracytoplasmic Sperm Injection (ICSI) if you have been trying to get pregnant for more than two years.

At HayatMed, we will help you to know whether you need a fertility treatment and, if so, which fertility treatment is most appropriate for you.

What is Intracytoplasmic Sperm Injection (ICSI)?

About half of the couples who are having reproductive problems, the cause of their problem is sperm-related. Intracytoplasmic Sperm Injection, or known as  ICSI, is the most commonly used treatment for infertile males.

ICSI procedure needs only one sperm, which is injected directly into the egg. Then the embryo is transferred to the uterus.

What is the difference between IVF and ICSI?

In Vitro Fertilisation (IVF) and Intracytoplasmic Sperm Injection (ICSI) are the most commonly used for fertility treatments. The main difference between them is the way that the sperm fertilizes the egg.

Fertilization using the IVF process is done by putting the egg and sperm in a dish to fertilize on their own. While using the Intracytoplasmic Sperm Injection procedure, one sperm is directly injected into the egg.

When is the Intracytoplasmic Sperm Injection recommended?

When is the Intracytoplasmic Sperm Injection recommended?

This method of treatment can help couples when the partner’s sperm:

  1. can’t get to the egg at all
  2. can reach the egg but can’t fertilize it.

The doctor will likely recommend ICSI process in the following circumstances:

  • The sperm count is meager.
  • A high percentage of sperm are abnormally shaped or slow.
  • The Sperm can not be shown in the semen sample but can be collected from the duct or the testicles where sperm are usually stored.
  • Your partner has problems with getting an erection and ejaculating caused by diabetes or other reasons.
  • There is a need to use frozen sperm that are not of the best quality.
  • There is a need to test the embryos to avoid passing on genetic problems.
  • If you have tried IVF before, you may move on to ICSI if eggs retrieved were not fertilized or if not enough eggs could be retrieved.

This technique can improve the chances of fertilization compared with IVF. However, it doesn’t guarantee that fertilization will happen.

What are the success rates of ICSI?

Fertilization success rates using Intracytoplasmic Sperm Injection are often higher compared with IVF fertilization success rates. However, pregnancy success rates are likely the same using both methods.

ICSI success rates are classified as follows:

  • 47 % if you are between 18 and 34
  • 40 % if you are between 35 and 37
  • 33 % if you are between 38 and 39
  • 24 % if you are between 40 and 42
  • 14% if you are between 43 and 44
  • 5 % if you’re 45 or more

Keep in mind that the younger you are, the more likely to get a healthy pregnancy. Contact us to get more information about our full inclusive fees package for Intracytoplasmic Sperm Injection (ICSI) treatment.

What are the risks associated with ICSI procedure?

Here are some of the risks associated with this procedure:

Risk of multiple pregnancies

Transferring more than an embryo to the uterus is associated with a 30 % to 35 % chance of becoming pregnant with twins and a 5 % to 10% chance of having pregnant with triplets or more.

Pregnancy with multiple embryos increases the chances of developing complications during pregnancy and delivery like gestational diabetes, preterm birth, preeclampsia, Cesarean delivery, and prematurity complications. Increased risk of miscarriage

Many fertility treatments’ patients would be at risk of miscarriage if low-quality sperms were used to fertilize the eggs.

Medication reactions

You may experience some problems caused by fertility medications, such as ovarian hyperstimulation syndrome. In addition to other complications like headaches and restlessness, hot flushes, and irritability.

Risk of congenital disabilities and health problems at birth

Studies indicate that both pregnancy assisted by fertility treatments and natural pregnancy lead to the same rate of congenital disabilities in babies.

The Intracytoplasmic Sperm Injection risk of having a child with abnormalities is so low(less than 1%)

Risk of embryos damage

During eggs fertilization, not all the eggs will develop into embryos, some of the eggs may be damaged. Fertilization success rates using ICSI range from 50 % to 80 %.

How is the Intracytoplasmic Sperm Injection procedure done?

How is the Intracytoplasmic Sperm Injection procedure done?

The doctor will start the Intracytoplasmic Sperm Injection treatment by prescribing fertility drugs that help to ovaries stimulation to develop several mature eggs for fertilization.

He or she will use ultrasound, and blood tests, to determine the time when your eggs are ready for collection. Then, you and your partner will undergo separate processes.

Your partner will be requested to produce a semen sample himself, by ejaculating on the same day as your eggs are collected.

If there is no sperm shown in the semen, or the partner is unable to ejaculate,

then your doctor will use a needle to extract sperm from :

  • The partner’s epididymis, in a process called percutaneous epididymal sperm aspiration (PESA)
  • The partner’s testicle, in a process, called testicular sperm aspiration (TESA).

This step will usually be performed under local anesthesia, so your partner will not feel any pain.

In case, the doctor does not get enough sperm using these techniques, he or she will take a biopsy of testicular tissue, which has sperm attached.

This procedure is called testicular sperm extraction (TESE). It is also performed under general anesthesia. Surgical sperm extraction is often done before the treatment cycle begins. The retrieved sperm will be frozen.

During egg retrieval, the doctor will remove your eggs using a needle that attached to an ultrasound probe. The doctor will give you progesterone to prepare the womb lining for transferring the eggs.

You’re likely to be sedated so you will feel comfortable. At the same time, the specialist will isolate individual sperm in the laboratory and inject them into individual eggs.

The fertilized eggs (embryos) need from one to five days in a laboratory to grow. Once the embryos are ready, the doctor will transfer one or two of them to your uterus using a catheter, which usually guided by ultrasound.

If all goes well, one embryo or two will attach to the wall of your uterus, and you will become pregnant. After about two weeks, you will take a pregnancy test.

Contact us to get more information about our full inclusive fees package for Intracytoplasmic Sperm Injection (ICSI) treatment.

When can you get the treatment result?

After two weeks of embryos transfer, your doctor will test a blood sample to detect whether you’re pregnant or not. If you’re pregnant, your doctor will pass you to a pregnancy specialist for prenatal care.

If you’re not pregnant, you’ll stop using medications and probably get your period within a week. If you don’t get your period, you should contact your doctor.

How long can you do another Intracytoplasmic Sperm Injection cycle after a failed cycle?

The doctor will determine a suitable time for a new cycle after the failed treatment attempt.

Sometimes, the patient may be able to begin another cycle immediately, while in other cases, the doctor may recommend a rest before starting the next cycle.

If you’re interested in trying another cycle of ICSI, your doctor will discuss your next step and explain how to improve your success treatment chances.

Fertility treatment in Turkey

Recently, Turkey has become one of the most destinations for Fertility treatment abroad.

There are about 150 clinics that offer different types of fertility treatments by the hands of experienced doctors at moderate costs.

Noteworthy that the laws in Turkey prevent egg, sperm, or embryo donation.  Accordingly, only using the couple’s eggs and sperm is allowed.

When you consider this type of treatment and start to find out more details, especially about the price, you will be surprised that the cost of fertility treatments in Turkey can be half of that in other countries like the USA, the UK, and the UAE. This issue is one of the reasons that make Turkey a destination to consider.

HayatMed medical group, located in Istanbul, Turkey, is one of the approved clinics in the Ministry of Health. We deal with most experienced doctors in Turkey’s infertility treatment field.

Contact us to get more information about our full inclusive fees package for Intracytoplasmic Sperm Injection (ICSI) treatment.


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